Wayne State University

Aim Higher

Graduate Programs

Department of Pharmaceutical Sciences

Eugene Applebaum College of Pharmacy & Health Sciences

Wayne State University

Detroit, MI 48202

pscgrad@wayne.edu

I. ADMISSION

Applications for all Wayne State University Graduate School programs must be completed online. To access electronic Admission Application Forms and General Instructions for applying to Ph.D. or Ed.D. Programs at Wayne State University: CLICK HERE

For answers to several frequently asked questions concerning admission to the Pharmaceutical Sciences graduate program: CLICK HERE

II. INTRODUCTION

The graduate program described herein represents a continuing effort by the Faculty of the Department of Pharmaceutical Sciences to provide contemporary and relevant graduate education in the Pharmaceutical Sciences.  This document reviews the areas of specializations offered, the curriculum and requirements for the M.S. and Ph.D. degrees and financial assistance.  A description of the Faculty Research Interests of each faculty member is available online.  The program ensures a curriculum which provides: basic coursework that forms the foundation for and complements the more specialized courses presented by the faculty; early exposure to faculty research; adequate time for selection of an advisor; and careful evaluation of the student's research and teaching abilities.

III. THE UNIVERSITY AND THE CITY

Wayne State University (WSU) is one of the largest urban universities in the nation and is considered one of the top three urban research universities.  The University is composed of twelve different colleges, one of which is the Eugene Applebaum College of Pharmacy and Health Sciences (EACPHS).  The EACPHS is adjacent to the campus of the Detroit Medical Center (DMC).  The DMC has a long standing relationship with WSU and is one of the primary locations for clinical training of students and health care professionals associated with WSU.

Wayne State University anchors the Cultural Centerwhich is home many of the most important institutions of the City of Detroit, including the Detroit Institute of Arts, the Detroit Historical Museum, the Detroit Public Library, the Detroit Symphony Orchestra, and the Detroit Science Center.  As home to professional athletic teams in all of the major sports as well as its cultural venues, the City of Detroit provides the social and cultural advantages of a great metropolitan area.  At the same time, the city is the hub of many routes to the nearby year-round outdoor recreational opportunities of Michigan and Canada, being surrounded by the Great Lakes and many smaller inland lakes and rivers. The University benefits greatly from the resources of the city while, conversely, through its research, consulting, and other services, the University enriches the city with knowledge acquired in the classroom and the laboratory.

IV. DEPARTMENT OF PHARMACEUTICAL SCIENCES

A. General Information and Background

The Department of Pharmaceutical Sciences offers the degrees of Master of Science and Doctor of Philosophy in the various areas of specialization. Applicants may be invited for personal interviews in some instances.

B. Baccalaureate Training

In general, the applicant must have an adequate background in biology, physics, calculus, and chemistry.  In most instances, candidates for admission who have earned a B.S. degree in pharmacy, chemistry, or the biological sciences possess adequate preparation.

C. Areas of Specialization

 Medicinal Chemistry.  Medicinal Chemistry is a multifaceted discipline that encompasses synthetic organic chemistry, natural products chemistry, enzymology, chemical biology, structural biology and computational methods, all of which are aimed at the discovery and development of new therapeutic agents.  Medicinal chemistry is by nature an interdisciplinary science, and practitioners have a strong background in organic chemistry, coupled with a broad understanding of biological concepts related to cellular drug targets.  Scientists in the field are well positioned to work as part of an interdisciplinary team that uses chemical structural principles to design effective drugs and diagnostic agents.

Pharmaceutics.  Pharmaceutics is concerned with the study of physicochemical and biological factors that determine the input, distribution and elimination of drugs in animals and man.  Thus, pharmaceutics involves the design of drug- and gene-delivery systems and elucidation of factors which alter drug disposition and pharmacologic response. Pharmaceutics is divided into two sub-disciplines: physical pharmacy and pharmacokinetics.  Physical pharmacy is that area which is concerned with the development of drug dosage forms.  Pharmacokinetics is concerned with factors which influence drug absorption, distribution metabolism and elimination.  Pharmaceutics research requires interdisciplinary approaches applying chemistry, engineering, mathematics and/ or material science to biological problems.

Pharmacology and Toxicology.  Pharmacology is the health science that encompasses the study of drug action mechanisms from inter- and intra-molecular reactions at the subcellular level to drug actions on physiological systems of the whole organism.  The science of Toxicology is concerned safety and health of humans, animals and the environment by understanding alterations in normal structure or function resulting from exposure to drugs, synthetic chemicals, or natural products.  As translational sciences, pharmacology and toxicology employ many of the principles and methods of anatomy, physiology, biochemistry, microbiology, immunology, behavior and biophysics.  Research advances in these areas have enabled graduate programs to provide highly trained and competent scientists in the various sub-disciplines of pharmacology and toxicology.

D. Admission Requirements and Application Procedures

The Graduate Division and the Dean for Graduate Studies have the overall responsibility for graduate admissions to Wayne State University.  Decisions concerning the admissibility of applicants are based on careful review of applications by the faculty, in consultation with the head of the academic division or department.  Admission procedures and requirements are described in detail in the Policies and Procedures for graduate programs in the Pharmaceutical Sciences.

Applications for all Wayne State University Graduate School programs must be completed online. To access electronic Admission Application Forms and General Instructions for applying to Ph.D. Programs at Wayne State University: CLICK HERE

Three letters of recommendation are required for all applicants.

E. Graduate Coursework

Graduate coursework within the Department includes a broad exposure to various areas within the Pharmaceutical sciences (Core Curriculum) as well as also intensive specialization within the area of the student's research interests. Thus, graduates from the Department of Pharmaceutical Sciences are well-rounded in all facets of the discipline and capable specialists in the area of their research. The Pharmaceutical Sciences PhD does not require a minor for graduation.

Core Curriculum

In addition to meeting course requirements as outlined in the Graduate Bulletin, all graduate students are required to register for selected courses from the list below. Note that PSC 6800 is a full semester course, while PSC 7010, 7020, 7030, 7700, 7710 and 7720 are eight-week mini courses.

These courses are required for all Pharmaceutical Sciences graduate students:

o   PSC 6800 Introduction to Research (2 cr)

o   PSC 7010 Advanced Drug Action and Safety - 1 (2 cr)

o   PSC 7020 Advanced Drug Discovery - 1 (2 cr)

o   PSC 7040 Advanced Drug Formulation and Delivery - 1 (2 cr)

Each student must select one advanced course from the list below:

 o  PSC 7700 Advanced Drug Action and Safety - 2 (2 cr)

o   PSC 7710 Advanced Drug Discovery - 2 (2 cr)

o   PSC 7720 Advanced Drug Formulation and Delivery - 2 (2 cr)

Elective Departmental Course Offerings by Area of Specialization

    a. Medicinal Chemistry

o   PSC 6000 Fundamentals of Drug Design

o   PSC 7850 Seminar in Medicinal Chemistry

o   PSC 7800 Research Techniques in Medicinal Chemistry

o   PSC 8650 Special Topics in Medicinal Chemistry

    b. Pharmaceutics

o   PSC 7810 Research Techniques in Pharmaceutics

o   PSC 7860 Seminar in Pharmaceutics

o   PSC 8040 Pharmacokinetics and Biopharmaceutics

o   PSC 8660 Special Topics in Pharmaceutics

    c. Pharmacology/Toxicology

o   PSC 6890 Toxicology/Adverse Drug Reactions

o   PSC 7100 Advanced Pharmacodynamics I

o   PSC 7110 Advanced Pharmacodynamics II

o   PSC 7120 Advanced Pharmacology I

o   PSC 7600 Drug Abuse Pharmacology

o   PSC 7820 Research Techniques in Pharmacology

o   PSC 7870 Seminar in Pharmacology

o   PSC 8670 Special Topics in Pharmacology

Relevant Courses Offered by Other Departments 

 * BMB 7010 General Biochemistry Lecture

 * BIO 6160 Molecular and Cellular Biophysics

 * CHM 6440 Computational Chemistry

 * CHM 7200 Organic Structures and Mechanisms

 * CHM 7220 Organic Reactions and Synthesis

 * CHM 7240 Organic Spectroscopy

 * CHM 7410 Statistical Thermodynamics

 * CHM 7430 Chemical Kinetics

 * CHM 7620 Metabolism: Pathways & Regulations

 * CHM 7640 Molecular Biology

 * CHM 7660 Biomolecular Interactions

 * PPR 7670 Clinical Pharmacokinetics

 * PSL 7010 Graduate Physiology I

 * PSL 7011 Graduate Physiology II

 * PSL 7600 Advanced Cardiovascular Physiology

 * PSL 7660 Neurophysiology

 * PSY 5050 Physiological Psychology

 * PSY 7090 Theories of Learning

 * PSY 7120 Biological Basis of Behavior

 * PSY 8080 Memory & Brain

 * CHE5350 Polymer Science

 * CHE7350 Polymer Solutions

 * CHE7370 Biomaterial Interfaces

 * BME 5310 Engineering Principles of Drug Delivery

 * BME 5320 Colloids and Interfaces: Fundamentals and Biomedical Applications

 * IBS7010 Biomedical Molecular Biology

 * IBS7020 Biomedical Cell Biology

 * PHC7210 Fundamentals of Cancer Biology

 * PHC7220 Cell and Molecular Biology of Cancer Development

 * RAD7000 Imaging Physics I

 * BIO5640 Cancer Biology

 * BIO6000 Molecular Cell Biology

 * PSL7215 Nanobioscience

 * MBG7010 Molecular Biology and Genetics

 * BMS 6100 Business of Biotechnology

Registration Requirements and Plan of Work

Each graduate student in the Department is required to register for a minimum of one credit hour during each semester (including summer) until such time as all degree requirements are fulfilled. Students, who have registered for the full number of thesis/dissertation research credits but have not completed their thesis, should register for one (1) credit of thesis/dissertation research under "audit" until their thesis is defended, and approved. Failure to register or to be granted a leave of absence may result in dismissal from the program.

The Plan of Work, which delineates the sequence of courses required for degree completion, must be submitted to the Graduate School by doctoral students prior to registering for courses in their fourth (4) semester in the program. Master's students must submit a Plan of Work to the College Graduate Officer prior to completing twelve (12) credit hours of coursework or prior to registering for courses in their fourth (4) semester, whichever comes first.

Seminar Attendance and Presentations

All students in the Graduate Program are required to attend the weekly Departmental Seminars. In addition to the public thesis/dissertation defense, each Master's degree student must present one (1) Departmental seminar and each Doctoral student must present a minimum of three (3) Departmental seminars.

Both Master’s and Doctoral students will register for one credit of seminar, PSC 7850, in the Spring/Summer semester of their first year to provide their first seminar. The seminar should be 30 minutes in length and describe a research experience during the first year in the graduate program. After the first academic year, all students will register each winter semester for 1 credit of PSC 7860.

Doctoral students should schedule their second seminar during the Winter semester of their second year. The seminar shall be on a topic not directly related to the student’s dissertation work. The topic will be selected by the student in concert with his/her research advisor and must be approved by that semester’s seminar coordinator not less than two weeks prior to the scheduled seminar. Furthermore, the student must make available to the Department a two-page outline or summary of the seminar, including pertinent references. The outline/summary must be approved by the semester’s seminar coordinator, who will deliver it to the Department faculty, students, and staff by e-mail not less than one week prior to the seminar. Failure to comply with this requirement shall result in a lowering of the student’s seminar grade by one full letter grade.

Doctoral students should scheduler their third seminar during the Winter semester of their third year subsequent to completion of the Qualifying Examination. The seminar shall be on the topic of the student’s dissertation research.

Leave of Absence

A leave of absence is defined as an absence from the Graduate Program of a duration of any length up to and including one (1) semester or longer. A leave of absence shall only be permitted for extenuating personal or medical reasons. A leave of absence for maternity reasons is considered a medical leave of absence.

Students requesting a leave of absence from the Graduate Program must submit a written request, approved by the student’s advisor, to the Chairperson of the Curriculum Sub-committee. Requests for medical leaves of absence must be accompanied by a signed affidavit from the student's physician. This shall contain an indication of the degree of impairment, date of initiation and anticipated duration. All requests for leaves of absence longer than two (2) weeks will be reviewed by the Chairperson of the Curriculum Sub-committee and the student notified in writing of the action.

Requests for extension of an authorized leave of absence shall be made following the same procedures as the initial request.

Students granted a leave of absence from the program may be required to do remedial work, depending upon the length of time the student is away from the program.

Unauthorized/unexcused absences may result in dismissal from the program.

Leaves of absence of students are subject to WSU policies for the Non-Represented employees, including the provisions of the Family Medical Leave Act.

Electronic Communication

Email is the official means of communication by the University and the Department.  While it is permissible and sometimes desirable to maintain other email accounts outside the university system, your AccessID@wayne.edu account is the only account officially recognized by the university and department, and is therefore essential.  It is a condition of appointment that you visit and maintains your AccessID email account regularly, and that mailboxes do not become too full to accept new emails.  You are asked to create an email name (or alias) that is easily recognized as associated with you.

F. Requirements for the Master of Science Degree

In addition to the policies described herein, M.S. students must fulfill all established requirements of the Graduate School described in the most recent issue of the University Graduate Bulletin.

Advisor and Advisory Committee. The Master's Research Committee serves to approve the student's thesis proposal, monitor progress toward completion of research requirements, and conduct the Master’s Thesis Defense.

Either one (1) member of the Research Committee or the Committee moderator shall be a graduate faculty member outside the Eugene Applebaum College of Pharmacy & Health Sciences. Master's degree students shall present written progress reports to their Research Committee members at least once a year. The Master's Thesis must receive the Research Committee's approval for defense prior to scheduling a date for the defense.

Master's Thesis Research Outline. The Master's Thesis Research Outline must be filed with the Graduate Officer of the Eugene Applebaum College of Pharmacy and Health Sciences after the applicant has been advanced to candidacy and before registration in more than four hours of PSC 8999 (Master's Thesis Research and Direction). The completed form must be accompanied by a prospectus describing the research project.

G. Requirements for the Doctor of Philosophy Degree

In addition to the policies described herein, doctoral students must fulfill all established requirements of the Graduate School described in the most recent issue of the University Graduate Bulletin.

Advisor and Advisory Committee. The advisor in consultation with the Dissertation Committee represents the Department in helping plan the student's program.  Additionally, the advisor shall sign the student’s Plan of Work, recommend candidacy, guide the student's research, approve the dissertation, serve on the Qualifying Examination Committee and Doctoral Dissertation Committee, arrange for the Qualifying Examination and Dissertation public lecture presentation-defense, and certify to the Graduate School that the degree requirements have been fulfilled.

The Dissertation Committee performs an integral function in the progress of a student through their graduate education and training. It is responsible for approving the Plan of Work, developing the oral qualifying examination, approving the advancement of the student to Doctoral Candidacy Status, approving the Doctoral Prospectus and final Dissertation, and providing strategic oversight of the dissertation progress. The Committee must meet at least two times per calendar year which must be documented in order for the student to progress.

The Dissertation Committee shall be formed by the student's advisor and shall consist minimally of three (3) Departmental members plus one (1) graduate faculty member from outside the Eugene Applebaum College of Pharmacy & Health Sciences. The expertise of the non-college member must be appropriate to the student's dissertation work. In the case of co-advisors from the Department, the minimum number of Department members shall be increased to four (4). Once Graduate School approval for the committee has been obtained, any changes in the committee composition will require written justification and approval. The Dissertation Committee shall be formed before a student has completed three (3) semesters in the program.

Qualifying Examinations. Before taking the Qualifying Examinations, the student must have filed a Plan of Work with the Graduate School. Qualifying Examinations for all students will comprise a two component, written examination, a core and a specialization portion that will be equally weighted. The first component will assess the student's ability to integrate the principles covered in the Departmental core courses and the Departmental Seminars. The second component will test the student’s mastery of material in the specific area of specialization which they have designated (Medicinal Chemistry, Pharmaceutics, or Pharmacology). Each portion of the written exam (Core and Specialization) will consist of eight (8) questions, of which six (6) must be answered by the student.

The written exam will be administered by the Curriculum Sub-committee, who will determine the participating faculty, select specific questions from those submitted by faculty, and determine the exact dates for the written exam. Participating faculty will generally be those who have presented didactic material in the core course and those involved in coursework in the specific area of specialization, but may include additional faculty at the discretion of the Committee and by recommendation of the faculty advisors.

For the specialization portion of the exam, the Sub-committee will request that faculty submit questions for use in the specialization components.  The Sub-committee will review all submitted questions and select eight (8) for each area of specialization. Similarly, questions will be solicited from faculty participating in the core courses, and eight (8) questions from among those submitted will be selected.

The written examination will be offered annually in the month of June and all students taking the written qualifying examination at that time will take the core exam and those within a chosen area of specialization will take the same specialization examination. To pass the qualifying examination, students must pass both the core and the specialization components. If a student fails either portion of the written Qualifying examination, the Committee will make specific recommendations as to admitting the student to a second examination of those parts failed (Core and/or Specialization) and specify any additional work to be completed prior to such an examination. Generally, re-examination should occur within six (6) months of failure of the initial examination.

A separate oral qualifying examination will not be required. The oral Dissertation Proposal defense will satisfy the requirement for an oral qualifying examination.

Dissertation Outline and Committee. Following successful completion of the Written Qualifying Examination, the student must prepare, the Graduate School Doctoral Dissertation Outline and Record of Approval Form. This form is approved by the student's Dissertation Committee and the Chairperson of the Curriculum Sub-committee. Following approval, the form is forwarded to the Graduate School for the Dean's approval.

Within six (6) months of successful completion of the Written Qualifying Examinations, the student must present for an oral defense of their Dissertation Proposal. The format of the Dissertation Outline must be that of a research plan intended for submission to an appropriate funding organization, e.g. National Institutes of Health, National Science Foundation. The outline should not exceed 15 pages and must include all elements expected for such a document. At the discretion of the dissertation advisor, a budget section may be included in the Dissertation Outline. At the oral defense, the Departmental Graduate Officer or designee will serve as moderator. If a student does not successfully pass the oral defense, then the student may request a re-examination which must be scheduled within six (6) months, but no earlier than four (4) months of the original defense date. Should the student not successfully pass the second oral defense, the student will be excluded from the graduate program.   

Thesis/Dissertation Repository

The Department serves as a central repository for all of its graduate student theses and dissertations. Each student upon successful defense of their thesis or dissertation must provide the Chair of the Curriculum Sub-committee with one complete copy of the document for binding and addition to the Departmental holdings.

H. Academic Progress Requirements

The Curriculum Sub-committee is responsible for the oversight and review of the Graduate Programs in the Department of Pharmaceutical Sciences. This Sub-committee, which is appointed by the Chairperson of the Department of Pharmaceutical Sciences, shall be composed of a membership which represents each of the areas of specialization in the department, and Chaired by the Departmental Graduate Officer. All members must be appointed as Regular Faculty of the Graduate School. In addition to general oversight of the programs, it is the responsibility of this Sub-committee to review and make recommendations to the Department Chairperson on the following matters:

   1. Annual review of the progress of all graduate students at the completion of the Fall and Winter semesters;

   2. All proposed new courses for the Graduate Program;

   3. All applicants for teaching assistantships; and

   4. All requests for leaves of absence from the Graduate Program. 

The post-Fall review will assess student’s academic performance primarily based upon grades achieved in courses. At the conclusion of the Winter semester, student performance will be evaluated in terms of coursework, research progress, fulfillment of University requirements for filing plan of work and thesis/dissertation outline, and overall professional advancement. This evaluation will include a written assessment by the faculty advisor of the student's strengths and weakness, as well as an indication of how any deficiencies will be addressed.

A student will be placed on probation for any of the following reasons:

   1. Conditional admission status;

   2. Obtaining a grade of less than B in any course;                                      

   3. Recommendation from advisor that the student is not making adequate progress in his/her research.

The student will be informed in writing, at the time of being placed on probation of the requirements for removal of probationary status. A student may be excluded from the program for any of the following reasons:

   1. Failure to comply with requirements set forth by the Curriculum Sub-committee;

   2. Receiving two (2) or more grades of less than B in any single semester.

Notice of probationary/exclusion status shall be made by written communication from the Chairperson of the Curriculum Sub-committee. A student may appeal the Sub-committee's actions by providing a written request for consideration to the Chairperson of the Sub-committee. This request should document extenuating circumstances which the student feels should be considered by the Committee in its deliberations. The written appeal must be received by the Sub-committee Chairperson within ten (10) calendar days after initial notification of probationary/exclusion status. The Sub-committee shall act on the student's appeal within 15 calendar days of receipt of the appeal. In the event that the Sub-committee cannot be convened within this time frame, the request for appeal will be acted upon by the Chairperson of the Department of Pharmaceutical Sciences.

The Curriculum Sub-committee may request repeating a course in which a letter grade of less than B is obtained. The Department policy is to limit to two the number of courses that graduate students may repeat during their graduate career at the Department of Pharmaceutical Sciences. Each course may be repeated once. Students may repeat only courses in which they received a grade of B- or below. The original grade for the course will remain on the student’s transcript, but only the second iteration of the grade will be used in calculating the student’s Grade Point Average. Students will not receive University financial aid for repetition of courses.

If a student fails to meet programmatic deadlines established by the Graduate School or by the Department, the Chairperson of the Curriculum Sub-committee may prevent course registration until the requirements have been fulfilled.

Specific assignment of letter grades and time-limits for conversion of I and Y grades are outlined in the Graduate Bulletin. In addition, a grade of Y shall not be given for seminar or laboratory research courses (i.e., PSC 7800, 7810, and 7820). In cases of withdrawal from a course (mark of W) or receipt of a grade of X, the student’s advisor shall provide a written explanation for the withdrawal as part of the academic progress review as outlined.

A letter grade of B- is not a satisfactory grade as stated in the Graduate Bulletin and may be cause for excluding a student from the program.

All students in the graduate program are strongly encouraged to seek external sources for funding their Graduate Research Assistantship. However, students receiving stipend support from the department will annually apply for stipend support from funding sources outside the Eugene Applebaum College of Pharmacy & Health Sciences. The student will document to the Curriculum Sub-committee their efforts on the written Annual Review of Student Progress form. Failure to do so is grounds for non-renewal of stipend support.

I. Selection of Advisors

If a student has not chosen an advisor at the time of entering the program, a faculty member appointed by the Chairperson of the Graduate Program Committee will serve as temporary advisor.  The student will be informed in writing of this temporary advisor appointment.  During the first semester the temporary advisor will encourage the student to meet with all faculty members of the discipline and have the student discuss his/her research interests with those of the faculty. MS degree students must choose a graduate advisor by the end of the first semester, whereas Ph.D. students must choose a graduate advisor by the end of their second semester.

J. Teaching Experience

It is the policy of the Department of Pharmaceutical Sciences that Ph.D. students in the graduate program be provided opportunities for supervised teaching experiences, including the presentation of lectures, assistance in student laboratory courses and the presentation of research seminars.

K. Research Publications and Presentations by Students

http://www.cphs.wayne.edu/psc/psc_phd_grads_all_082712.xlsProductive research projects result in publishable findings, and student publication of research is an expectation. Students are expected to present their research findings at national and regional research conferences.  Both the Department of Pharmaceutical Sciences and the Graduate School offer support for graduate students to present at meetings.  In addition, graduate student support to attend relevant scientific meetings and conferences is also available through individual faculty research awards.

L. List of Ph.D. Recipients (1969-Present)

The Department has graduated a total of 72 Ph.D. recipients since the inception of the program.  A listing of recipients can be obtained by clicking here

M. Student Financial Aid Programs

Graduate students in the Department of Pharmaceutical Sciences are eligible for financial assistance from a number of sources. Although other sources also exist, graduate support is derived from primarily the following:

Rumble Fellowship. Sponsored by the Graduate School, the recipient of this award receives a graduate tuition waiver, a living stipend, health insurance and subsidized housing in University graduate housing.

Graduate Research Assistantship.   Sponsored by the Graduate School and by Individual Faculty. Individual faculty members can sponsor students as Graduate Research Assistants. The recipient of this award receives a graduate tuition waiver, a living stipend, and health insurance, however, are not required to assist Departmental faculty in teaching.

Graduate/Professional Scholarship.  Sponsored by the Graduate school, the recipient of this award will receive either a graduate tuition waiver or a tuition waiver plus a living stipend.

Frank O. Taylor Scholarship Award.  An award provided annually to an outstanding graduate student in the Department, who aspires to a career in the pharmaceutical industry.  

George Fuller Endowed Scholarship. Full time students working toward their PhD in the Pharmaceutical Sciences are eligible for this award, established by the friends and family of alumnus and former dean, George Fuller.  Applicants must be in good academic standing, yet need not demonstrate financial need. 

The names of past recipients of the Frank O. Taylor and George Fuller scholarships can be obtained by clicking here

Student Employment in a Faculty Laboratory. Graduate students are also eligible to serve as paid hourly assistants (up to 20 hours/week) in the laboratory of a faculty member.

N. Research Facilities and Environment

The Department of Pharmaceutical Sciences, located in EACPHS, is well-equipped for the conduct of contemporary research in medicinal chemistry, pharmacokinetics, drug delivery, biochemical pharmacology, molecular biology, neuropharmacology, drug metabolism, and toxicology.  Among the major pieces of analytical equipment housed in and near the Department are a 400 MHZ NMO, an LC-MS-MS, DNA synthesizer, several high performance liquid chromatographs, gas chromatograph with a mass spectrometry interface, as well as nuclear magnetic resonance, infrared, atomic absorption and ultraviolet/visible spectrophotometers.  Computer-assisted drug design in medicinal chemistry is facilitated by the availability of a complete molecular modeling system. In addition, the Department has facilities and equipment for studies utilizing radioisotopes and cell/tissue cultures and for work in neuropharmacology and behavioral pharmacology.  Located nearby is the Department of Chemistry, which houses the Wayne State University Chemistry Research Instrument Facility, including several mass spectrometers, with both GC and LC interfaces, NMRs and a DNA synthesizer. Researchers in the Department also have access to the services provided by the Macromolecular Core (for both sequencing and synthesis) and Flow Cytometry facilities in the EACPHS. The department also has a state-of-the-art inhalation exposure facility for small animals for toxicological studies.

WSU Libraries offer reference and research support, interlibrary loan, circulation and course reserve services, document delivery and library and information literacy programs.  The libraries utilize and support the latest information technologies to provide state-of-the-art access to instructional and research materials, and provide a range of study environments from silent to interactive and include a 24-hour facility.  The Vera Parshall Shiffman Medical Library is located adjacent to the School of Medicine at the Detroit Medical Center, and the Science Library is located nearby on Main Campus. The Learning Resources Center, located within EACPHS, maintains a library of major journals and books relevant to the Pharmaceutical Sciences and is an integral part of the university library system.